Abstract

Abstract Nanopharmaceuticals and nanonutraceuticals research has been lately receiving a lot of scientific attention. We aimed to identify the top 100 most cited original articles of the scientific area, analyze their research themes, major contributors regarding authors, institutions, countries and journals. The bibliometric data was extracted from the Web of Science electronic database. Data was further processed by a bibliometric software, VOSviewer, to generate bubble maps to visualize the results. Inter-institutional and international collaboration networks were constructed to further understand the cooperation between different study centers. Results revealed that over 60% of the articles were published in the 2000s. As of November 2019, the articles were cited 576–3665 times, with 20.1–261.8 citations per year. The majority of the most prolific institutions were based in the United States. Besides the United States, China, South Korea, Canada and Germany contributed heavily to the 100 articles. Some popular themes included drug delivery, tumor, toxicity/biocompatibility and biodistribution. Regarding composition materials, gold, silver and polymeric nanoparticles were the most commonly used.

Highlights

  • According to the European Commission, nanomaterials stand for “materials which often have specific properties due to their small particle size” (European Commission, 2019)

  • Nanopharmaceuticals and nanonutraceuticals research has been lately receiving a lot of scientific attention

  • The majority of the most prolific institutions were based in the United States

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Summary

Introduction

According to the European Commission, nanomaterials stand for “materials which often have specific properties due to their small particle size” (European Commission, 2019). They can be described as products of nanotechnology with at least one dimension between 1 and 100 nm (De Jong and Borm, 2008). Our recent analysis of the biotechnology research literature identified nanotechnology and nanoparticles to be among the trending research themes (Yeung et al, 2019a). Due to their size-dependent properties, nanomaterials are being widely used. The nanomaterials are regarded as chemical substances; they are regulated in Europe by the EU REACH (European Regulation on Registration, Evaluation, Authorization and Restriction of Chemicals).

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