Abstract
AbstractBy combining nanocatalysis with base catalysis, a novel one‐pot multistep process was found for the synthesis of substituted heterocycles of biological relevance from simple substrates. The process is based on the initial Au/O2 oxidation of allylic alcohols, which is followed by base‐catalyzed tandem hetero‐Michael/aldolization/crotonization with ortho‐hydroxy‐ or ortho‐aminobenzaldehydes. The flexibility of the reaction even allowed the benzaldehyde partner to be prepared in situ in an example of a one‐pot/five‐step process.
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