Bibliometric Analysis and Knowledge Mapping of Research Trends in Brugada Syndrome

Abstract

Background: Brugada Syndrome (BrS) has been extensively studied over the last 30 years, warranting a review of its research landscape, including prevalent themes and potential future directions. Objective: By employing bibliometric analysis, this work seeks to map the current state and trajectory of BrS research, highlighting key contributors and unexplored areas while suggesting avenues for future studies which could propel the field forward. Methods: This paper analyzed BrS-related articles from 1992 to 2023, extracted from the Web of Science core collection, using tools like CiteSpace, VOSviewer, Pajek, and Scimago Graphica to examine research output, geographies, authors, affiliations, keywords, and citation patterns. Results: Out of 3,713 BrS publications, the US has been the most prolific, with the Netherlands producing the highest caliber work, and China ranking fourth in output. The University of Amsterdam emerged as the leading institution. Pedro Brugada topped the author list. The journal Circulation led in citations, with an impact factor of 37.8, indicative of its JCR Q1 status and elite ranking. Keyword analysis revealed ‘Brugada syndrome’ (2756), ‘Sudden death’ (1387), and ‘St-segment elevation’ (1200) as common terms, with ‘Management,’ ‘Guidelines,’ ‘Consensus conference,’ and ‘Genetics’ as up-and-coming topics. Conclusions: Stable research funding and publication rates indicate a mature phase for BrS research, with genomics, proteomics, biomarkers, clinical prediction models, and gene therapy poised as future focal points.