Abstract

The process of skin repair after injury is complex and fragile. Deficiencies in any of its phases can lead to the formation of chronic nonhealing wounds. Diabetes mellitus is often a major contributing factor for chronic wounds, which cause significant suffering in patients, and are a serious burden for healthcare providers. The management of chronic diabetic wounds remains a considerable challenge; therefore, the search for an effective treatment is of great importance. Erythropoietin (EPO) is generating increasing interest for promoting wound healing and may lead to the development of a new paradigm for treatment of wounds. This article focuses on the beneficial effects of EPO on tissue regeneration during the

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