Abstract
Ten ovarian stromal tumors (fibromas and thecomas) associated with free peritoneal fluid were compared with 60 similar lesions in patients devoid of fluid at laparotomy. The tumors were studied microscopically and one, associated with fluid, was examined by electron microscopy. There appears to be a critical relationship between the mass volume of solid tissue and surface area of a given tumor, and a significant component of distinctive myxoid tissue in determining the presence or absence of free fluid. Tumors smaller than 10 cm. in diameter were not associated with fluid nor were larger tumors lacking myxoid tissue. No explanation relating to the formation of fluid was found ultrastructurally. Our observations favor transudation of extracellular fluid from the stroma through the thin capsular surface as the basic mechanism.
Published Version
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