Abstract
A 31-year-old man was admitted to the ICU with a diagnosis of primary pulmonary hypertension and severe hypoxemia caused by hemoptysis. Examinations revealed 112/56mmHg of systemic artery pressure, 113/54mmHg of pulmonary artery pressure and a PaO2/FIO2 ratio of 87. Continuous intravenous infusion of PGE1 and dopamine worsened the pulmonary hypertension. Continuous intravenous infusion of PGE1 and amrinone improved pulmonary hypertension (75/53mmHg; vs. systemic artery pressure 110/70mmHg) and raised the PaO2/ FIO2 ratio to 300.The patient died of massive hemoptysis several days later, however amrinone may be an effective agent for treating primary pulmonary hypertension.
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