Abstract
There is a number of Synthetic (allopathic) drugs which are used in the treatment of mental disorders, they are helpful but synthetic drugs also have lots of side effects with monetary problem. The Ayurveda has a long tradition of treating mental disorders. Herbal drugs are playing a significant role in the health care agendas worldwide, mostly due to the general faith that they are without any side effects, besides being contemptible and locally available. Recently there is a recovery of an interest in herbal medicines for the management of different aliments including CNS disorders. Experimental screening of ethanolic extracts of Stem & root of Amaranthus spinosus for brain disorders was done by Anti-stress activity (Swimming endurance test, Anoxia stress tolerance test and Immobilization stress test) Nootropic activity (Elevated plus maze and the Morris water maze). It was concluded that the hydro alcoholic extract of Amaranthus spinosus stem & root (200, 400 mg/kg) has anti-stress and nootropic activity in dose dependent manner.
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