Abstract
In this work, we investigated the behavior of CuO nanoparticles (NPs) in simulated gastrointestinal juices. It was found that CuO NPs agglomerated significantly in the gastric and small intestine phases, with a higher agglomeration in the small intestine than that in the gastric phase, which was consistent with the results on zeta potentials. Dissolution experiment showed that CuO NPs released more Cu2+ in the gastric phase (pH = 2.5) than that in the small intestine phase (pH = 7). This was due to much lower pH in gastric juice, leading to higher dissolution of CuO NPs.
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Schedule a callMore From: IOP Conference Series: Earth and Environmental Science
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