Behavior of antioxidant parameters in young cattle during the course of the year

Abstract

To analyze the behavior of antioxidant parameters in young cattle over 1 year and to detect possible health-related deficits during certain periods. Every 2 months over the course of 1 year, six healthy 12-month-old Holstein Friesian/German black and white heifers underwent a clinical examination and blood samples were obtained. The 36 animals were kept in tie-stalls during September, November, January, March and July, and solely at pasture in May. The antioxidant parameters superoxide dismutase (SOD), glutathione peroxidase (GPX) and the Trolox equivalent antioxidant capacity (TEAC), hematocrit and the metabolic parameters β-hydroxybutyrate, bilirubin, cholesterol, protein, albumin, urea, haptoglobin, calcium, inorganic phosphate, iron, alkaline phosphatase, aspartate transaminase, glutamate dehydrogenase and creatine kinase were determined. The GPX activities in September and January were significantly lower than those from March till July. The TEAC concentrations were in particular lower in January and significantly lower in March than in September and November. Differing SOD activities were not statistically significant. The correlation between SOD and GPX during the entire period was significant as well as between SOD and TEAC throughout the year except in January, whereas GPX and the TEAC only significantly correlated in November and from March till July. Albumin significantly correlated with the TEAC. The metabolic parameters were within the physiological range at all times, except urea in November and July and phosphate in May. The young cattle showed significantly reduced GPX activities from September to January, and reduced TEAC concentrations particularly in January and March. Decreased GPX activity is indicative of a low selenium supply. Among other disadvantages, this is unfavorable for the development of heifers. A reduced provision with antioxidant agents, particularly vitamin E and β-carotene, is indicated by the TEAC and has negative effects that are comparable to those caused by a lack of selenium. In terms of health prophylaxis, particularly during winter, specific attention should be given to the supply of sufficient trace elements and good quality silage.