Abstract
Method Twenty female Sprague Dawley rat (SD rat) were randomly divided into two groups according to their bedding types. The 1 group was raised in wood shaving bedding as a control and 2 one was in corncob bedding as an endocrine disrupting agent. Each group was checked daily for the first day of vaginal opening, and their vaginal smears were collected to determine estrous cyclicity after vaginal opening. The interval between vaginal opening and the first normal estrous cycle was recorded for determining sexual maturation. The phases of normal estrous cycles were as follows, proestrus, estrus, metestrus and diestrus. We compared the proportion of normal estrous cycles in each group.
Highlights
into two groups according to their bedding types
The 1st group was raised in wood shaving bedding as a control
2nd one was in corncob bedding as an endocrine disrupting agent
Summary
From 8th APPES Biennial Scientific Meeting Darwin, Australia. 29 October – 1 November 2014. Aims Recently, many experimental animal studies have demonstrated several adverse effects of endocrine disrupting agent, such as reduced reproductive behavior, altered estrous cycle, and decreased slow-wave sleep. The purpose of this study was to compare the pubertal progression in wild type female rats according to different bedding types. Method Twenty female Sprague Dawley rat (SD rat) were randomly divided into two groups according to their bedding types. The 1st group was raised in wood shaving bedding as a control and 2nd one was in corncob bedding as an endocrine disrupting agent. The interval between vaginal opening and the first normal estrous cycle was recorded for determining sexual maturation. The phases of normal estrous cycles were as follows, proestrus, estrus, metestrus and diestrus. We compared the proportion of normal estrous cycles in each group
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
