Abstract
The effect of a beclomethasone dipropionate nasal spray on middle ear effusion was tested in a double-blind study of drug vs placebo (vehicle). Seventy children, aged 4–14 years, sprayed each nostril twice daily for one month. Among them 35 received a daily dose of 400 μg of the beclomethasone. The results of tympanometry, audiometry and otomicroscopy were compared in the two groups, and the statistical analysis revealed P-values around 0.5. The conclusion is that the active drug had no effect on middle ear effusion in the population investigated.
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