More Votes for Therapeutic Nihilism

Abstract

Afrin nasal spray did not aid eustachian tube function in a double-blind study of children with severe eustachian tube dysfunction. This result should discourage widespread use of such drugs for this condition. As mild dysfunction has not been studied, conclusions cannot be drawn about use for this condition. There have been no studies showing efficacy; use of topical nasal decongestants should await such studies. A double-blind study revealed no benefit of this drug. "The conclusion of this study is clear: beclomethasone nasal spray has no effect on a middle ear effusion in preschool and school children." Comment: Perhaps other doses, means of administration, etc, would be helpful, but proof of efficacy is still lacking. My patients don't get this therapy (nor the previous one).