Abstract
Background: Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. Objective: Our purpose was to determine the effect of bath-PUVA therapy on SA. Methods: Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment. Results: All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm 2 ). Ultrasonography showed significant reduction in both skin thickness and density. Conclusion: Bath-PUVA therapy appears to be effective in the treatment of SA.(J Am Acad Dermatol 1998;38:240-2.)
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