Abstract
Balance disorders include a large number of syndromes and diseases that affect the central or peripheral vestibular pathways, the cerebellum, or the sensory pathways associated with proprioception. Such disorders usually present with one of two mayor symptoms: vertigo or ataxia. The aim of this chapter is to offer a general overview of the pharmacotherapy of balance disorders, that we have classified in three major categories: acute vestibular syndrome, episodic vestibular disorders and persistent balance disorders. Episodic vestibular disorders include motion sickness, benign paroxysmal positional vertigo (BPPV), vestibular migraine, Meniere disease and vestibular paroxysmia. Among persistent balance disorders we have considered persistent postural-perceptual dizziness (PPPD) and mal de debarquement syndrome (MdDS). Pharmacotherapy of balance disorders is still in its infancy and further randomized clinical trials are needed to control vertigo and ataxia in central and peripheral disorders.
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