Bacteriological profile of urinary tract abnormalities children with urinary tract infection

Abstract

Objective To investigate the clinical characteristics, pathogens and drug resistance in urinary tract abnormalities children with urinary tract infection. Methods In a retrospective and observational study between January 2012 and December 2016, children with urinary tract infection were recruitment. Based on radiographic test, patients were divided into the normal urinary tract group and the abnormal urinary tract group. Results Four hundred and seventy six cases were included, and 162 were identified with urinary tract abnormalities, of which the most common diagnosis (43.83%) was hydronephrosis. Male children with urinary tract abnormalities were subjected to recurrent urinary tract infection (UTI). Fever was the most common clinical presentation. A total of 166 strains of pathogenic bacteria were detected, and gram-negative bacteria were ranking the first (71.08%). E. coli and Enterococcus were responsible for 40.36% and 22.89% children with UTI, respectively. However, enterococcus faecalis were more frequently detected in children with urinary tract abnormalities. There were no significant difference in bacteria resistance to common use antibiotics between the two groups. Conclusion Male children with urinary tract abnormalities were the risk factor for UTI, especially infection with enterococcus. Key words: Urinary tract infection; Urinary tract abnormalities; Pathogens; drug resistance