Bacteriological profile of surgical site infections and its resistogram in Sangli district, Maharashtra

Abstract

Introduction: Surgical site infection (SSI) is one of the most common hospitals acquired infection. The present study describes resistogram of bacterial pathogens in SSIs in the hospitals in and around Sangli, Maharashtra, India. Materials and Methods: The resistogram pattern was studied by modified Kirby-Bauer disc diffusion method. Results: A total of 1491 pus samples from patients clinically diagnosed of SSIs were processed and 911 isolates were obtained. The most common Gram-positive isolates were Staphylococcus aureus(53.92%), coagulase-negative Staphylococci (31.17%), Enterococcus (10.58%), and Streptococcus pyogens (4.31%); while Gram-negative isolates were Escherichia coli (33.16%), Klebsiella spp. (28.92%), Citrobacter species (4.98%), Pseudomonas aeruginosa (12.96%), Acinetobacter species (1.99%), Proteus mirabilis (10.97%), and Proteus vulgaris (6.98%). The frequency of methicillin-resistant S. aureus (MRSA) was 28% whereas the frequency of methicillin sensitive S. aureus was 72%. The MRSA showed multidrug resistance pattern. Conclusion: Twenty-eight percent are MRSA which showed multidrug resistance pattern. While most of the Gram-positive isolates were resistance toward the amoxicillin/clavulanate, gentamicin, and ceftriaxone. Most of the Gram-negative isolates were resistant to ampicillin, ciprofloxacin and ceftriaxone.