Abstract

The biomedical application of low temperature atmospheric pressure plasma (LTAPP) is a collaborative interest for engineering, medical, dental and biological researchers. This laboratory study tested whether LTAPP can limit growth of Porphyromonas gingivalis, a periodontal pathogen strongly associated with periodontal disease, disease progression, and refractory periodontitis. Methods: After extensive pilot trials, the study consisted of 24 agar plate samples of P. gingivalis- 20 samples were exposed to LTAPP at 5, 7, 9 and 10 minutes and 4 control samples were exposed to helium gas only. Immediately after exposures, the samples were incubated anaerobically for 72 hour at 37°C. After 72 hours, zones of inhibition were measured. Results: After 5, 7, 9, and 11 minutes of exposure times, results reveal a statistically significant difference in the bactericidal effect of the LTAPP on P. gingivalis compared to control bacteria not exposed, as measured by zone of inhibition (cm) (p0.0001). Differences in the bactericidal effects were significant for each pair of consecutive time points: 5 minutes verses 7 minutes, 7 minutes verses 9 minutes, and 9 minutes verses 11 minutes (p= 0.0360, p= 0.0009, and p0.0001, respectively).

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.