Bacterial Isolates and Antimicrobial Susceptibility from 400 Burn Patients

Abstract

Burn wound infection continues to be the most common cause of burn mortality. Identifying of the bacterial isolates and their antimicrobial susceptibility is an important step in controlling burn infection. Four hundred burn patients with 2470 culture specimens were retrospectively by reviewed. Pseudomonas aeruginosa (10.6%) was the most common isolate, susceptible to imipeneim-cilastatin (90%) and cefatazidime (81%);followed by Enterococcus species (9.6%), susceptible to ampicillin (91%) and vancomycin (73%); Staphylococcus epidermidis (5.9%), susceptible to vancomycin (91%) and cefamandole (79.5%); and Staphylococcus aureus (5.4%), susceptible to vancomycin (99%) and cefamandole (65%). The main side effects of topical agents were leukopenia (7.5%) with silver sulfadiazine and pain (85%) with mafenide acetate. Morbidity among the burn patients included sepsis (13.5%), severe wound infection (5%), and pneumonia (5%). The mortality rate in this series was 5.3%.