Analysis of bacterial distribution and drug sensitivity of chronic suppurative sinusitis

Abstract

Objective To investigate the bacterial distribution and drug sensitivity characteristics of chronic suppurative sinusitis. Methods Nasal secretions of 89 cases of chronic suppurative sinusitis patients before operation were collected in this study, and nasal secretions were culture in medium.Disk diffusion method(Kirby-Bauer,K-B)was used for drug sensitivity test.Sensitivity of bacteria strain to cefazolin, ceftazidime, cefepime, imipenem, meropenem, vancomycin, cefoperazonesulbactam, ciprofloxacin and other antibiotics were analyzed. Results After the submission of purulent secretion specimens of nasal meatus in 89 cases chronic suppurative sinusitis patients with sticky, we found that 80 of the patients were detected bacteria. The positive rate was 89.89%(80/89).80 patients were detected in 82 strains of bacteria,a total of 15 species,of which 1 cases of nasal meatus sticky purulent secretion specimens there were 2 strains of bacteria.In 15 kinds of staphylococcus aureus were detected bacteria, staphylococcus aureus, escherichia coli, pseudomonas, enterobacter aerogenes,5 kinds of bacteria occupy the top 5,respectively,accounted for 21.95%,18.29%,14.63%,13.41%,10.98%.Drug sensitivity test of staphylococcus aureus showed that all of the staphylococcus aureus was sensitive to vancomycin, the sensitivity was 100%; the sensitivity of cefazolin, ceftazidime, cefepime, imipenem, meropenem, cefoperazone sulbactam, ciprofloxacin and other antibiotics were 0.00%.All the staphylococcus epidermidis were sensitive to imipenem, meropenem, vancomycin, cefoperazone sulbactam, the sensitivity was 100.00%;followed by cefazolin,the sensitivity was 86.67%,and to ceftazidime, cefepime, ciprofloxacin sensitive, were all below 30.00%. Escherichia coli,pseudomonas aeruginosa and enterobacter aerogenes and other gram negative bacteria were sensitive to imipenem,meropenem,the sensitivity was 100.00%. Conclusion The bacterial infection in patients with chronic suppurative sinusitis pathogens, including staphylococcus epidermidis, staphylococcus aureus, escherichia coli, pseudomonas, enterobacter aerogenes, bacterial culture positive to vancomycin, imipenem, meropenem, cefoperazone Shubatan, cefazolin and antimicrobial susceptibility, and so on antimicrobial treatment but should closely monitor the antimicrobial spectrum of change, in order to adjust the medication. Key words: Suppurative sinusitis; Bacteria; Antibiotics; Sensitivity