Abstract

Direct deposition of the negatively charged polyelectrolyte, carboxymethyl cellulose (CMC), into a bacterial cellulose (BC) matrix was used as a simple route to fabricate a re-swellable and biocompatible cellulose-based hydrogel. As a result of this non-destructive approach, the physical and mechanical property of the original BC were well-preserved within the resulting BC/CMC hydrogel. As a BC/CMC-based colorimetric pH sensor, it exhibited a rapid response with an easy color differentiation between each pH by the naked eye, and wide linear range of pH 4.0–9.0 with good linearity. For the detection of glucose in sweat, the BC/CMC-based colorimetric glucose sensor provided a low limit of detection (25 μM) with a wide linear detection range (0.0–0.5 mM) and high accuracy. These BC/CMC based sensors could potentially be applied as non-invasive semi-quantitative sensors for on-skin health monitoring.

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