Abstract
European Journal of ImmunologyVolume 52, Issue 9 Back CoverFree Access Back cover story: Eur. J. Immunol. 9'22 First published: 01 September 2022 https://doi.org/10.1002/eji.202270098AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Our colourful back cover features heat-map-like graphics representing MHC class II HLA-DR surface expression in human melanoma MelJuSo cells transfected with single microRNA molecules (red: up-regulating; purple: down-regulating). The image is taken from Houseman and Huang et al. (pp. 1452–1463), where the authors introduce a flow cytometry-based high-throughput RNAi screening for microRNAs regulating HLA-DR surface expression in MelJuSo cells. Plate-based data normalization and transformation of Median Fluorescence Intensity (MFI) measurements were performed, and the MFI data have been computed into robust z-scores across three independent experimental replicates and displayed as heat map colours. Volume52, Issue9September 2022 RelatedInformation
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