Abstract
Orbital atherectomy prior to stenting (OAptS) of severely calcified coronary artery stenosis (CCAS) may improve procedural and clinical outcomes. However, there is little data comparing in-hospital outcomes between genders. Patients who underwent OAptS between 2016-2021 at 7 participating IU Health hospitals were identified in the Indiana University Health Multicenter Cath Registry. Clinical data and procedural characteristics were collected as defined by the National Cardiovascular Data Registry criteria then analyzed according to gender. In-hospital data from 608 patients (426 male and 182 female) were analyzed. Overall, group characteristics were similar. Females had a higher proportion of diabetes (62% vs 51%, p=0.012), smaller average stent diameter (2.8 +/- 0.8mm vs. 2.9 +/- 0.7mm, p=0.008), and shorter average lesion length (41 +/- 22mm vs 46 +/- 24mm, p=0.01). In general, clinical and procedural outcomes were not significantly different between males and females (Table 1). However, females did have a significantly higher incidence of coronary artery perforation (2.2% vs. 0.5%, p=0.048). In conclusion, our study shows both men and women have low overall adverse event rates and comparable clinical outcomes. While women had a higher risk of coronary perforation, it was not associated with worse clinical outcomes or increased mortality.
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