Abstract
Ventricular electrical activity delay (VED) using high frequency ECG(HFECG) provides greater accuracy in estimating the left ventricular (LV) septo-lateral conduction delay than mere QRS duration. Real time measurement identifying microvolt ECG data in 250-500 Hz refines patient choice verifies electrical resynchronisation. Procedural delays are frequent due to lack of real time feedback. To design a wearable device that would provide cardiologists with real time streaming data of HFECG from 150-500 Hz in uV range. A portable wearable 5x5 cm ECG patch is used to sample raw ECG at 1000 samples per second. The Device resolution is 286 nV, floor noise 3 uV, filter amplification 1uV√Hz.nData is filtered with proprietary algorithms. Display is done with Hilberts transform. The original signal of ECG and the extracted envelope are synchronised and presented for clinical analysis. 55 consecutive patients were screened and consented for the study, 52 had normal ECGs and were recruited. Analysis of data used to study the Hf-ECG (150-250 Hz) show details presented. HFECG was extractable in 94.54% of the patients. 3 people out of 55 had noisy ECG from which HfECG was not visible by our algorithms. Amplitudes of Hf-ECG in various leads are in fig. Maximum voltages were obtained in V2 and V5. The limb leads had the smallest amplitudes of HFECG, and was extractable only in lead 3. Beat to beat recording of HFECG and resultant calculation of VED can be done with great accuracy and speed using our novel device thereby opening up a frontier for the use of the same in clinical practice, in choice of patients for CRT and His bundle pacing and real time during the procedure.
Published Version
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