B lymphocytes taken to task: a role for a background conductance K2P K+ channel in B cells. Focus on “Expression of TASK-2 and its upregulation by B cell receptor stimulation in WEHI-231 mouse immature B cells”

Abstract

the pivotal role played by K+ channels in lymphocyte biology has long been recognized ([4][1]). Two K+ channels have been reported in T and B lymphocytes, a voltage-gated Kv1.3 (or KCNA3) channel and the Ca2+-dependent IK1 (KCNN4) channel. These K+ channels are involved in the intracellular Ca2+