Abstract
Researchers at Women and Children's Hospital of Buffalo, NY, report an 11- year-old boy with a history of developmental delay who developed transient agitation and choreoathetoid movements of upper extremities in temporal relation to treatment of influenza A and B respiratory infections with oral azithromycin on 2 occasions.
Highlights
Metabolic brain network patterns differentiate subjects with TS from controls, as well as a second pattern that differentiates TS subjects with OCD from those without OCD
The brain networks involve regions associated with motor activity as well as those regions associated with behavioral changes
Dr Katie Kompoliti of Rush Med Sch, Chicago comments that this study identifies TS-related abnormal network patterns that encompass multiple interacting nuclei instead of isolated regions, a view of the whole "elephant," not just the trunk or tail. (Neurology March 15, 2011;76:938-939)
Summary
Metabolic brain network patterns differentiate subjects with TS from controls, as well as a second pattern that differentiates TS subjects with OCD from those without OCD. The brain networks involve regions associated with motor activity as well as those regions associated with behavioral changes (anterior cingulate and prefrontal cortex). Dr Katie Kompoliti of Rush Med Sch, Chicago comments that this study identifies TS-related abnormal network patterns that encompass multiple interacting nuclei instead of isolated regions, a view of the whole "elephant," not just the trunk or tail.
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