Abstract
A severely microcephalic, quadiplegic child without extracranial anomalies was born to a young non-consanguineous couple. Ultrasonographic examination at 15 weeks of the second pregnancy revealed a biparietal diameter that corresponded to 13 weeks, although the other measurements were in accordance with 15 weeks9 gestation. Further examination at 20 and 24 weeks revealed progressive microcephaly. The aborted fetus (at 24 weeks9 gestation) was grossly microcephalic, but lacked further abnormal findings. Antenatal ultrasonographic diagnosis of autosomal recessive microcephaly is feasible, at least in a proportion of cases.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have