Automatic controlling the tissue temperature during treatment of deep tumor: A numerical study using finite element method

Abstract

Several methods of treating unhealthy cell in human tissue are used by the physicians. Transferring the heat to the infected cell is one of the methods to remove that cell. Point heating is an available technique to transfer heat to the infected cell. But in this technique, there is a possibility to damage the healthy tissue nearby the infected cell. Only controlling the temperature of the applicator cannot save the unhealthy tissue from damage. In this paper, the two dimensional finite code for bio-heat equation has been developed to measure the temperature during the treatment of point heating. Pennes bio heat equation is the main mathematical model for the transient heat transfer analysis considered in this research. Three cases of point heating techniques are considered to study the temperature profile of the tissue using the developed code. Those are constant point heating, step point heating and temperature controlled point heating. The tissue temperature controlled point heating is designed to restrict the healthy tissue temperature below the damage threshold temperature. Using the temperature profile, tissue damage rate is measured with the help of Arrhenius rate equation. Among these three techniques tissue temperature controlled point heating is shown as better one. The outcome of this research will be helpful for the physicians as well as bio-medical engineer.