Abstract
AbstractPurpose:To evaluate complications and anatomical retention when using autologous ear cartilage as a carrier in type 1 Boston keratoprosthesis (Kpro) surgery. Methods: In New Zealand White r...
Highlights
Purpose:To evaluate complications and anatomical retention when using autologous ear cartilage as a carrier in type 1 Boston keratoprosthesis (Kpro) surgery
This experimental study attempted to evaluate the use of auricular cartilage as the carrier to fix the Boston keratoprosthesis and prevent carrier melt, a devastating postoperative complication which leading to aqueous leaks or extrusion of the device
Rabbit 1 (PMMA backplate) In rabbit 1, who had received the Kpro with a polymethyl methacrylate (PMMA) backplate, neovascular tissue was found over the carrier cartilage at 8 days post-implantation
Summary
Purpose:To evaluate complications and anatomical retention when using autologous ear cartilage as a carrier in type 1 Boston keratoprosthesis (Kpro) surgery. Dr Zhang has developed a keen interest in ophthalmology She is currently undertaking research on ocular surface disease and Keratoprosthesis. Polymethylmethacrylate is well tolerated by the cornea, the incidence of corneal carrier melt around stem varies from 10% to 18%. This experimental study attempted to evaluate the use of auricular cartilage as the carrier to fix the Boston keratoprosthesis and prevent carrier melt, a devastating postoperative complication which leading to aqueous leaks or extrusion of the device. Despite the recent advances in the Kpro, some of these keratoprosthesis patients develop sterile ulcerations and thinning of the corneal tissue, which acts as a carrier for the Kpro, especially those with autoimmune disease. Keratolysis of the donor cornea remains a rare, yet devastating, postoperative complication that leads to exposure of the eye to pathogens, perforation, leakage of the aqueous humor, and extrusion of the Kpro. (Robert & Dohlman, 2014)
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