Abstract
Cellular therapies for critical limb ischemia (CLI) have been shown in multiple reports to improve perfusion and limb salvage where patients were deemed unsuitable for conventional therapy. The procedure which involves bone marrow aspirate for CLI requires a comprehensive understanding of vascular disease to allow for appropriate patient selection, preprocedure planning, intraoperative marking, and delivery of the cellular concentrate in a perivascular space under continuous ultrasound guidance. The clinical trials to date, in the majority of patients, have the bone marrow aspiration performed by a hematologist. The remainder of the service description is performed by the vascular specialist. However, some centers prefer that one
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