AUTOIMMUNE DISEASES ASSOCIATED WITH SJÖGREN SYNDROME

Abstract

<h3>Objectives</h3> To discuss the association between other autoimmune diseases (AID) and secondary Sjögren syndrome (SSS). <h3>Study Design</h3> A literature search was performed between 2002 and 2017 using the following databases: PubMed, Bireme, and Google Scholar. <h3>Results</h3> Rheumatoid arthritis is more frequently associated with SSS, so these patients should be followed due to the possibility of developing SSS. SSS pathogenesis is different from other AIDs, once it is not related to the severity of associated AID, but probably to how long it has been present. In 2016, a consensus defined new diagnostic criteria for patients with xerophthalmia and xerostomia, and questions were created to screen for patients needing further exams. A score was also developed. It is not possible to determine the main factor leading to AID manifestation, but each AID is related to specific genes that may change the defense cells' mechanism of action. Treatment is symptom-related and consists of stimulating the production of secretion from the injured glands and using various lubricating agents. <h3>Conclusions</h3> SSS oral manifestations added to the symptoms of other AIDs affect the patient physically and psychologically, so multidisciplinary treatment is essential to warrant a better quality of life.