Autobiographical Memory and Future-Oriented Thinking in Recurrent Major Depressive Disorder

Abstract

Event Abstract Back to Event Autobiographical Memory and Future-Oriented Thinking in Recurrent Major Depressive Disorder M J King1, 2, B. Levine3, A G MacDougall2 and M C McKinnon1, 2* 1 St. Joseph's Healthcare , Mood Disorders Program, Canada 2 McMaster University, Department of Psychiatry and Behavioural Neurosciences, Canada 3 Rotman Research Institute, Canada Autobiographical memory (AM) and future-oriented thinking are thought to rely upon the same underlying neural substrates and cognitive processes. A substantial number of studies reveal overgeneralization, by which AM comprises primarily factual or repeated information in patients with major depressive disorder (MDD). We examined whether this lack of AM specificity in MDD is influenced by participant’s mood state (i.e., euthymic versus depressed) at the time of event encoding. Participants were also asked to imagine positive, negative and neutral future events. Using the Autobiographical Interview, participants with recurrent MDD and matched controls were asked to recall an event encoded during i) positive ii) negative/depressed and iii) neutral/euthymic mood state. Future-oriented thinking was tested using a modified Crovitz cue word paradigm. Results showed that whereas patients with MDD recalled fewer episodic details of events encoded during positive and euthymic mood states, episodic recall for events encoded during a depressed state was enhanced. Controls showed the opposite pattern, where episodic recollection was highest for events encoded during a positive mood state and lowest for events encoded during a negative mood state. Patients imagined less specific and less vivid future events than controls, regardless of emotional valence. Conference: The 20th Annual Rotman Research Institute Conference, The frontal lobes, Toronto, Canada, 22 Mar - 26 Mar, 2010. Presentation Type: Poster Presentation Topic: Psychiatric Citation: King M, Levine B, MacDougall A and McKinnon M (2010). Autobiographical Memory and Future-Oriented Thinking in Recurrent Major Depressive Disorder. Conference Abstract: The 20th Annual Rotman Research Institute Conference, The frontal lobes. doi: 10.3389/conf.fnins.2010.14.00159 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 01 Jul 2010; Published Online: 01 Jul 2010. * Correspondence: M C McKinnon, St. Joseph's Healthcare, Mood Disorders Program, Hamilton, Canada, mmckinno@stjoes.ca Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers M J King B. Levine A G MacDougall M C McKinnon Google M J King B. Levine A G MacDougall M C McKinnon Google Scholar M J King B. Levine A G MacDougall M C McKinnon PubMed M J King B. Levine A G MacDougall M C McKinnon Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.