Improvement in memory deficits following computer assisted cognitive remediation in patients with a mood disorder

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Event Abstract Back to Event Improvement in memory deficits following computer assisted cognitive remediation in patients with a mood disorder G. B. Hall1, 2, G. M. MacQueen3, 4, M. C. McKinnon1, 2 and L. Meusel1, 2* 1 St. Joseph's Healthcare , Mood Disorders Program, Canada 2 McMaster University, Department of Psychiatry and Behavioural Neurosciences, Canada 3 Calgary Health Region , Department of Psychiatry, Canada 4 University of Calgary, Department of Medicine, Canada Background: Major depressive disorder (MDD) and bipolar disorder (BD) are characterized by impairments in cognitive performance across multiple domains, impacting quality of life in these individuals. Cognitive remediation interventions designed to target neuropsychological deficits have been successfully implemented for patients with schizophrenia, however only one study has explored their efficacy for patients with MDD. Methods: Patients with MDD or BD completed a 10-week cognitive remediation program aimed at improving cognitive performance across four domains: attention, memory, psychomotor speed, and executive function. Cognitive functioning was assessed with a battery of standardized neuropsychological tests at baseline and immediately following the intervention. Results: Mixed-effects linear modeling showed greater relative improvement on memory tasks (delayed verbal recall, p = .05; backward digit span, p= .04; digit symbol subtest front, p= .04 and back, p= .004) in patients receiving the cognitive remediation intervention (n= 18) relative to wait-listed patients (n = 18) and a healthy control group (n = 18). Conclusions: Findings from this study will help establish the utility of cognitive remediation programs for patients with a mood disorder. Implementation of such programs may eventually translate into decreased medical-related disability and better functional outcome for patients with illness-related cognitive impairment. Conference: The 20th Annual Rotman Research Institute Conference, The frontal lobes, Toronto, Canada, 22 Mar - 26 Mar, 2010. Presentation Type: Poster Presentation Topic: Neurorehabilitation Citation: Hall GB, MacQueen GM, McKinnon MC and Meusel L (2010). Improvement in memory deficits following computer assisted cognitive remediation in patients with a mood disorder. Conference Abstract: The 20th Annual Rotman Research Institute Conference, The frontal lobes. doi: 10.3389/conf.fnins.2010.14.00109 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 29 Jun 2010; Published Online: 29 Jun 2010. * Correspondence: L. Meusel, St. Joseph's Healthcare, Mood Disorders Program, Hamilton, Canada, lmeusel@stjoes.ca Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers G. B Hall G. M MacQueen M. C McKinnon L. Meusel Google G. B Hall G. M MacQueen M. C McKinnon L. Meusel Google Scholar G. B Hall G. M MacQueen M. C McKinnon L. Meusel PubMed G. B Hall G. M MacQueen M. C McKinnon L. Meusel Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.