Abstract
Abstract: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by challenges in social communication and the presence of repetitive behaviors and restricted interests. It is acknowledged as a complex, multifactorial disorder influenced by both genetic and nongenetic factors. Recent advancements in neuroimaging studies have provided valuable insights into the observable changes in the brains of individuals with ASD. It is estimated that worldwide, about 1 in 100 children has autism. This estimate represents an average figure and reported prevalence varies substantially across studies. This review aims to explore factors influencing prevalence rates, highlighting the significant roles played by both genetic and environmental factors in the development of ASD. Furthermore, a recent study delved into the cellular structure, size, and shape of the brains of ASD individuals, revealing notable differences across various brain regions. The disparities were particularly pronounced in certain areas. While educational and behavioral treatments have traditionally been primary in managing ASD, there is growing recognition of the potential benefits of pharmacological and interventional approaches. This review strives to elucidate the diverse pathophysiological mechanisms contributing to the onset of Autism, as well as to provide insights into therapeutic interventions for the condition, emphasizing a multifaceted approach to treatment.
Published Version
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