Abstract
Much health benefits by lactic acid bacteria (LAB) have been observed via in-vivo trials. LAB’s health benefits are described such as improving of intestinal microbial balance between probiotics and harmful bacteria, protecting of pathogen infection and modulating of host’s immunity in gut. Colorectal cancer (CRC) located in intestine and its development leads to invade or spread to other parts of the body result in death. Recent many publications about LAB have demonstrated the immense potential as alternative bio-therapeutics. Actually, LAB have been reported to be the safe bio-therapeutic with positive effects against various cancer types including CRC. In this review, we discuss the evidences of beneficial effects of LAB application and its molecular mechanisms.
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