Abstract
Thank you for your comments on our work. As you mentioned, it is sometimes difficult to distinguish hypertrophic cardiomyopathy (HCM) from athlete's heart. Delayed gadolinium enhancement (DGE) in cardiac magnetic resonance (CMR) and plasma brain natriuretic peptide (BNP) levels may be useful to detect high risk HCM patients in young athletes. However, changes in these parameters may be smaller in young HCM patients than in our study population (mean age 67.4 years). Moreover, cardiac hypertrophy progresses rapidly in young people, especially in adolescence [[1]Maron B.J. Spirito P. Wesley Y. Arce J. Development and progression of left ventricular hypertrophy in children with hypertrophic cardiomyopathy.N Engl J Med. 1986; 315: 610-614Crossref PubMed Scopus (262) Google Scholar]. A single examination of CMR and/or BNP may not be sensitive enough to exclude high risk HCM in young people. Further studies are necessary to establish the usefulness of DGE in CMR and/or plasma BNP levels for diagnosing HCM in young athletes.
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