Abstract

The effects of a number of organic reagents on the structure of the mitotic apparatus (MA) of several invertebrate eggs were investigated. In general, the agents induced either a large increase in the volume and retardation of the MA (hexylene glycol, dimethylsulfoxide, etc.) or caused it to partially or completely disappear (formamide, dithiodiglycol, dimethylacetamide, etc.). The immediate effects of the agents on the MA were reversible, but reversibility of embryonic development was only obtained if the eggs did not remain in the reagent for too long a time. The analysis of the specific effects of these agents suggests that the eggs utilized possess a pool of unoriented (or unpolymerized) MA material which may be reversibly affected by the agents studied. In the case of augmenting agents, the material is oriented into the MA or into aster-like bodies, in the case of dispersing agents, the material returns to the pool. Although no decision could be made as to whether the agents act directly or indirectly on the MA, the totality of the observations support the latter possibility.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.