Abstract
The presence of metaplastic ossification within a atypical lipomatous tumour /well differentiated Liposarcoma (ALT/WDLPS) is a rare occurrence. We report a case ALT/WDLPS with unusual extensive metaplastic bone formation in a 30 years female who complained of swelling in the right shoulder for the past one and a half years.
 Bangladesh Journal of Medical Science Vol.20(1) 2021 p.197-199
Highlights
Atypical Lipomatous Tumor (ALT) is a malignant tumor comprising of fat and variable number of spindle cellswith hyperchromatic nuclei and multi vacuolated lipoblasts
Atypical lipomatous tumor with osteoid metaplasia – a rare occurrence spermatic cord being called as well differentiated liposarcoma (WDL).2The so called ALT have higher rates of complete surgical excision, lower rate of local recurrence and lower risk of undergoing dedifferentiation as compared to WDL.[2]
ALT is confirmed by ring and giant marker chromosomes composed of amplified material from the long arm of chromosome 12, and florescence in situ hybridization, this was not done in our case
Summary
Atypical Lipomatous Tumor (ALT) is a malignant tumor comprising of fat and variable number of spindle cellswith hyperchromatic nuclei and multi vacuolated lipoblasts. Differential diagnosis included lipoma with central calcified fat necrosis, osteolipoma, chondrolipoma, pleomorphic lipoma, liposarcoma with osteoid differentiation and liposarcoma with osteosarcomatous differentiation. Presence of lipoblasts ruled out a benign diagnosis. Absence of cartilage and presence of variably sized adipocytes with atypia ruled out chondrolipoma and osteolipoma respectively.
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