Abstract
The primary therapeutic approach for severe secondary mitral regurgitation (MR) in combination with atrial fibrillation is often not clear. To create atherapeutic guideline for daily clinical practice based on acase report as well as basic literature. If afunctional component is suspected, restoration of sinus rhythm may lead to asignificant improvement in MR. The extent of the improvement and the time required to achieve this improvement are often difficult to predict. The involvement of an electrophysiologist is recommended in order to assess the likelihood of successful long-term rhythm control aimed at improving MR. In unclear cases, cardioversion combined with short-term administration of antiarrhythmic medication may be useful to demonstrate potential improvement of MR in sinus rhythm.
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