Abstract
Heart failure with preserved ejection fraction (HFpEF) frequently coexists in patients with atrial fibrillation (AF). This close relationship is unsurprising given the shared risk factors and pathophysiological mechanisms underlying both conditions.1 However, the clinical implications of HFpEF in patients with symptomatic AF remain unclear. Specifically, the efficacy and safety of rhythm control strategies in patients with coexistent HFpEF is uncertain. Growing evidence suggests that catheter ablation is an effective treatment for heart failure with reduced ejection fraction (HFrEF),2 but evidence in patients with HFpEF remains sparse.
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