Abstract
1. 1. Normal animals contained 133 ± 9 nmoles ATP/g wet weight. During prolonged anoxia (24–72 hr) a considerable percentage (up to 60 per cent) of this level was maintained. 2. 2. The energy production is thought to be realized by means of a mechanism called anoxic endogenous oxidation where the oxidative agent is the lipochrome pigment of the cytosomes. Quantitative calculations of the possible energy production based on the redox potential of the pigment agree well with the maximal ATP level observed during anoxia. 3. 3. The mechanism of endogenous oxidation is activated by the gradual decrease of oxygen tension in the environment, whereas the acute total oxygen shortage cannot activate.
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