Atherosclerosis, Segmental Involvement and Grading of Luminal Narrowing of Coronary Artery: A Autopsy Study

Abstract

Background and Objectives: Atherosclerosis is a complex disease contributing to increased mortality. The exact global incidence of atherosclerosis is beyond calculation. Autopsy studies can provide information about the impact and course of atherosclerosis. Methods: 50 heart specimens with aorta up to its bifurcation were obtained from medico-legal autopsies. Sections from representative areas were studied for gross and microscopic evidence of atherosclerosis. Percentage of variations compared with other studies. Results: Heart specimens were obtained from medico-legal autopsies. Sections from representative areas were studied for gross and microscopic evidence of atherosclerosis. Interpretation and Conclusion: Among the 50 cases studied, 35 were males and 15 were females. Coronary arteries of 24 males (72.72%) and 9 females (27.27%) showed atherosclerosis. Males were affected more than females. Age has a dominant influence on atherosclerosis. Among coronaries, left anterior descending artery is most commonly involved. Autopsy studies give occurrence of atherosclerosis. This study will help radiologists and interventional cardiologists, in diagnosis and treatment. The incidence of atherosclerosis in developing countries is same as developed countries.