Abstract
To determine the difference in macular choroidal thickness (CT) profile between eyes in healthy individuals using swept-source optical coherence tomography. Cross-sectional noninterventional study. One hundred and forty eyes from 70 healthy patients with spherical equivalent between ± 3 D and with difference ≤ 0.25 D between eyes were scanned using a swept-source optical coherence tomography (Topcon Corporation). Cross-sectional noninterventional study. One hundred and forty eyes from 70 healthy patients with spherical equivalent between ± 3 D and with difference #0.25 D between eyes were scanned using a swept-source optical coherence tomography (Topcon Corporation). A horizontal CT profile of the macula was created in both eyes by manually measuring the subfoveal CT from the posterior edge of retinal pigment epithelium (RPE) to the choroid/sclera junction. Three determinations were performed at successive points 1,000 mm nasal to the fovea and 5 more temporal to the fovea. The differences in CT between both eyes were analyzed. Mean age was 25.4 ± 19.9 years (from 4 to 75). The mean spherical equivalent was 0.18 ± 1.37 D (from -3 to +3). Mean macular nasal CT was thicker in the right eye (RE) than in the left eye (LE) (228.11 ± 69.23 μm vs. 212.27 ± 62.71 μm; P = 0.0002; Student's t-test paired data). Mean subfoveal CT and mean temporal CT was not statistically significantly different between the eyes. No statistically significant differences were observed comparing spherical equivalent in the RE compared with the LE. Both men and women showed a thicker mean nasal choroid in the RE versus the left (men, 226.97 ± 61.56 μm vs. 209.87 ± 60.31 μm; women, 229.63 ± 79.39 μm vs. 215.47 ± 66.68 μm, P = 0.003 and P = 0.03, respectively; Student's t-test paired data). At each nasal determination, CT in the RE was statistically significantly thicker than the LE (N1: 283.72 ± 81.10 μm vs. 269.76 ± 75.81 μm [P = 0.001]; in N2: 230.45 ± 73.47 μm vs. 211.33 ± 66.92 μm [P = 0.0002]; and in N3: 170.16 ± 61.00 μm vs. 155.72 ± 53.87 μm [P = 0.008], respectively). To the best of our knowledge, this is the first report suggesting thicker macular nasal choroid in the RE compared with the LE. In contrast, subfoveal CT and temporal CT were not found to be different between eyes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
