Association of resting heart rate with dyslipidemia

Abstract

Objective To investigate the association between resting heart rate（RHR）and dyslipidemia. Methods A total of 772 subjects（average age：40. 1 ± 11.8 years;male：74. 7%）were recruited by random sampling method from medical checkup population. The survey data included resting heart rate,blood lipid and other metabolic parameters. The subjects were divided into three groups according to the RHR,as RHR 〈 70 bpm,70 bpm ≤ RHR 〈 80 bpm,RHR ≥ 80 bpm groups. Results RHR were positively correlated with triglyceides （TG）,as well as total cholesterol（TC）（r = 0. 316 and r = 0. 110 respectively,all P value 〈 0. 05）. Low RHR had no significant correlation with HDL-C or LDL-C. The prevalences of hypertriglyceridemia and hypercholesterolemia increased significantly with RHR elevation（χ2 = 7. 214 and 5. 285 respectively,all P value 〈 0. 05）. By logistic regression analysis,adjusted for BMI,gender,serum creatinine,serum uric acid,fasting blood glucose and age,we found that compared with RHR 〈 70 bpm group,the odds ratio（OR）values for hypertriglyceridemia was 1. 540 （95%CI：1. 086-2. 185,P=0. 016）in 70 bpm≤RHR 〈80 bpm group and 1.640（95% CI：1.067 -2.523,P =0. 024）in 80 bpm ≤ RHR group,and the OR values for hypercholesterolemia was 1.197（95 % CI： 0.749 - 1.913,P=0.453）in70 bpm≤RHR 〈80 bpm group and 1.814（95% CI：1. 036-3. 177,P =0.037）in 80 bpm≤RHR group. Conclusions RHR is independently and positively correlated with the prevalence of hypertriglyceridemia and hypercholesterolemia and the blood levels of both lipid. RHR has no significant correlation with HDL-C or LDL-C level. Key words: Hypertriglyceridemia Hypercholesterolemia Resting heart rate