Abstract
Associations of phenotypic signs of undifferentiated connective tissue dysplasia (UCTD) and bone fractures not related to postmenopausal, senile or glucocorticoid osteoporosis are discussed. A cross-sectional study enrolled 458 persons (143 had a history of fractures). A significant predominance of individuals with fractures in the UCTD group was revealed. Strong positive correlations of the total number of fractures with the number of external signs of UCTD (p<0.0001), internal signs of UCTD (p<0.0001), Beighton joints hypermobility index (p<0.0001) were found. Weak positive correlations of the number of fractures with the height (p=0.02) and arms span (p=0.011), and the personal smoker index (p=0.01) were revealed.
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