Association of osteopontin with thyroid dysfunction in type П diabetes mellitus

Abstract

Both thyroid diseases (TD) and diabetes mellitus are common endocrine disorders that often appear in clinical practice (DM). It is more common for persons with type 2 diabetes to have hypothyroidism or hyperthyroidism (T2DM). A considerable influence on blood glucose, lipid, and protein metabolism, as well as many other organs and tissues, is exerted by thyroid hormones in the blood (T2DM). It has been shown that in people with hyperthyroidism, the presence of osteopontin increases, and in those with hypothyroidism, it decreases, indicating that it may be a novel way to find thyroid illness. A total of one hundred twenty (120) subjects were included in current study. Variables like (gender, age, BMI, thyroid hormones, FBS, HbA1c, lipid profile and OPN) were recorded and documented from participant included in this study. The results of current study displayed there was a significant differences between osteopontin and body mass index in patients suffering from thyroid dysfunction with diabetes (-0.37) with (P≤0.05), T3 was (0.32) and FBS was (0.35) both of them recorded significant differences and (P≤0.05) in patients with diabetes type II. TSH, T3 and T4 findings were high significant differences with OPN in patients with thyroid dysfunction with diabetes with (-0.89), (0.9) and (0.89) respectively. While other parameters recorded no-significant differences.