Association of neck circumference and lipid profile and its effect in predicting dyslipidemia in type 2 diabetes: Beijing Community Diabetes Study (BCDS-10)

Abstract

Objective To investigate the association between neck circumference and lipid profile in Chinese individuals with type 2 diabetes. Methods Total of 2410 subjects with type 2 diabetes (age 20-80 yrs) were recruited from 15 community health centers in Beijing using a multi-stage random sampling approach. Dyslipidemia was diagnosed according to 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. Results (1)The study sample consisted of 986 men and 1424 women with a mean neck circumference of (36±4)cm. Mean total cholesterol, triglyceride, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol was (5.2±1.1)mmol/L, (1.8±1.2)mmol/L, (1.3±0.4)mmol/L and (3.0±0.9)mmol/L, respectively. (2)Neck circumference correlated positively with triglyceride (men(r=0.093), women(r=0.077), P 0.05). Receiver operating characteristic analysis showed that the area under the curve for neck circumference and low-density lipoprotein cholesterol was 0.527 for men and 0.519 for women (P>0.05). Conclusion In the present study, neck circumference is related with lipid profile in Chinese individuals with type 2 diabetes, especially triglyceride and high-density lipoprotein cholesterol. Neck circumference might be used in a clinical setting as an indicator for screening or evaluating dyslipidemia in type 2 diabetic subjects. Key words: Diabetes, type 2; Neck circumference; Dyslipidemia; Community