Abstract

Objective: Matrilin-3, a structural protein of the cartilage extracellular matrix, has a role on chondrocyte proliferation. Gene alterations of matrilin-3 may cause skeletal and chondro-cartilage diseases like Temporomandibular joint internal derangements Therefore, the aim of this study is to investigate whether matrilin-3 gene (MATN-3) alterations are associated with TMJ internal derangements or not.

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