Abstract
Objective: To determine the association of preeclampsia and vitamin D deficiency.
 Study design: Cohort study.
 Place and duration of study: Gynecology Department, Khwaja Muhammad Safdar Medical College, during 01-07-2018 to 31-12-2018.
 Material and Methods: In this study the pregnant females irrespective of their gravida and parity status and having gestational age more than 20 weeks were included. The cases that had vitamin D level lower were labelled as cases and those with normal levels as controls. They these cases were followed monthly until delivery and during this period they were followed for protein urea and BP to label pre eclampsia.
 Results: In this study 100 cases were selected. 50 in each group. Mean age in case and control group was 29.57±4.57 vs 28.43±3.79 years and mean duration of gestation at presentation was 26.43±5.11 vs 27.42±5.23 weeks. There were 39 vs 41 multigravida and 37 vs 38 uneducated females in cases and control group respectively. Preeclampsia was seen in 4 (08%) of control and 14 (28%) cases with odd ration of 4.47 (1.35 to 14.75) with p value 0.01.
 Conclusion: There is significant association of low vitamin D level and risk of pre eclampsia.
 Key words; pre eclampsia, vitamin D, Hypertension.
Highlights
Preeclampsia (PE) is one of the highly morbid and can be fatal entitiy if converted into eclampsia
There is further data regarding the co administration of calcium alomg with vitamin D and that is even been recommended by World Health Organization (WHO) in the prevention of pre eclampsia.[7,8]
Dietary factors are one important aspect of the offending factors that can result in hypertensive disorders like pre eclampsia and among them role of vitamin A, C and D have been seen in the past and great emphasis is being given to the latter one
Summary
ASSOCIATION OF LOW VITAMIN D WITH PRE ECLAMPSIA. Dr Nazia Tufail[1], Dr Sadia Shafiq[2], Dr Qudsia Nawaz[3], Dr Nosheen Bano[4], Dr Munazzah Bashir[5], Dr Sumreen Anjum[6 1,4] MBBS, FCPS, Assistant Professor Gyne and Obs, Khwaja Muhammad Safdar Medical College, Sialkot. 2,5MBBS, FCPS, Assistant Professor Gyne and Obs, M.Islam Medical College, Gujranwala. Dr Nazia Tufail[1], Dr Sadia Shafiq[2], Dr Qudsia Nawaz[3], Dr Nosheen Bano[4], Dr Munazzah Bashir[5], Dr Sumreen Anjum[6 1,4] MBBS, FCPS, Assistant Professor Gyne and Obs, Khwaja Muhammad Safdar Medical College, Sialkot. 2,5MBBS, FCPS, Assistant Professor Gyne and Obs, M.Islam Medical College, Gujranwala. 3MBBS, FCPS, Assistant Professor Gyne and Obs, CMH, Lahore 6MBBS, FCPS, Consultant Gyne and Obs, Medix Hospital, Lahore
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