Association of inflammation with female reproductive system disorders

Abstract

Inflammation is the body response against infection, injury and illness. It is a significant factor which can affect reproduction processes. Inflammatory state has key roles in physiological reproductive functions in women like menstruation, ovulation, implantation and pregnancy. Previous studies evaluated the association of inflammatory mechanisms with disorders such as ovulatory abnormalities, polycystic ovary syndrome, endometriosis, premature onset of labor and infertility in women—the present review summarized association between inflammation state and some reproductive disorders in female. Based on available findings, the inflammation state can be associated with various female reproductive disorders, which finally can affect fertility potential. Thus, assessment of inflammatory mechanisms and their association with processes of reproductive in treatment strategies of female infertility can be efficient. More comprehensive studies with a large number of patients and consideration of inflammatory pathways are required to provide more definitive evidences.