Association of gastric hyperplastic polyps with synchronous colorectal neoplasia

Abstract

Objective To evaluate the association of gastric hyperplastic polyps with colorectal neoplasia. Methods Data of consecutive patients who underwent esophagogastroduodenoscopy(EGD) and colonoscopy between January 2011 and December 2013 were reviewed retrospectively. They were compared with patients without gastric polyps who also underwent EGD in the same period. The relationship between gastric polyps and colorectal neoplasia was analyzed. Results The incidence of colorectal neoplasia in gastric hyperplastic polyps group was higher than that of the control group[24.0%(46/192) VS 10.4%(40/384), P=0.000]. An increased incidence of colorectal adenomas in gastric hyperplastic polyps group was found, but there was no difference in the incidence of colorectal cancer in gastric hyperplastic polyps group and control group[2.1%(4/192) VS 2.3%(9/384), P=1.000]. Stratification analysis suggested that the incidence of colorectal neoplasia in gastric hyperplastic polyps group who aged over 50 was significantly higher than that in the control group[28.5%(43/151) VS 10.6%(29/274), P=0.017], regardless of different genders and the number of gastric hyperplastic polyps. Conclusion The incidence of colorectal neoplasia in gastric hyperplastic polyps has significantly increased, especially in those aged over 50 years, regardless of different genders and the number of gastric hyperplastic polyps. Such patients should undergo colonoscopy to detect colorectal neoplasia. Key words: Gastroscopes; Colonoscopes; Gastric hyperplastic polyps; Colorectal neoplasia